string(16) "en/equipment/710" Circular Dichroism Spectrometer-Shenzhen Medical Academy of Research and Translation
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Technical Parameters | Sample Submission Requirements | Application Areas
Circular Dichroism Spectrometer

Circular Dichroism Spectrometer

Brand:

Applied Photophysics

Model:

Chirascan V100

Affiliated Platform:

Sample Preparation and Analysis Core Facility

Placement:

Weiguang Life Science Park 1A Building 310

Contact Person:

Xie Xingqiao，Lin Xuezhen

Phone:

13671959351，15625063726

Email:
Instrument Reservation
Technical Parameters Sample Submission Requirements Application Areas

Circular Dichroism (CD) Module

Light Source: 150W Xenon lamp

Spectral Dispersion Principle: Dual-polarization prism method

Effective Detection Wavelength Range: 175 nm - 1200 nm, single detector, no switching required

Wavelength Accuracy: ±0.1 nm (160-500 nm); ±0.5 nm (500-1200 nm)

Wavelength Repeatability: ±0.05 nm (160-500 nm); ±0.1 nm (501-1200 nm)

Wavelength Resolution: 0.01 nm

Stray Light: < 3 ppm (200 nm)

CD Resolution: < 0.00001 mdeg

CD Noise Level: ≤ 0.050 mdeg

CD Measurement Range: ±9000 mdeg

Temperature Control System: -40°C to 150°C, accuracy: ± 0.1°C


Stop-flow Circular Dichroism and Stop-flow Absorption Detection Module

Includes three sample mixing modes, with a minimum dead time of ≤1.2 ms

Temperature control range: -20°C to 80°C

Standard sample observation cell volume: 20 µL

Software includes data acquisition, real-time display, and result data analysis functions

Drive method: Pneumatic

Time distribution includes various modes such as logarithmic distribution, segmented distribution, and linear distribution

Stop-flow Fluorescence Detection Module: Wavelength range: not narrower than 185-850 nm

Stop-flow Fluorescence Polarization Detection Mode: Wavelength range: not narrower than 185-850 nm

Standard sample observation cell with dual light paths


Array-type Fluorescence CCD Detection Module (Three-level Structure)

The same sample can simultaneously acquire CD, Absorption spectra, Fluorescence excitation spectra, and Emission spectra.

Fluorescence emission spectrum range: 200~990 nm.

Dynamic linear range: 85,000:1.

Fluorescence spectral scanning time: less than 10 seconds.


This module is widely used in the study of molecular structure, molecular interactions, especially in the research of biological macromolecules, their interactions with small molecules such as drugs, and various chiral compounds. Applications include protein folding, protein conformation studies, DNA/RNA reactions, enzyme kinetics, and measurement of optical activity and purity of substances.

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