The Core Facility serves as a fundamental support platform for Shenzhen Medical Academy of Research and Translation (SMART). It is a centralized management platform for large-scale shared scientific instruments and equipment, established to meet researchers’ needs for producing innovative, high-impact outcomes and to support industrial development, while improving equipment utilization efficiency. Through resource sharing and complementary strengths, the Core Facility supports original innovation and the development of critical technologies and key instruments. It also aims to cultivate a hub for high-level technical professionals and skilled specialists in the fields of life sciences and medicine. By providing advanced and efficient services, the Core Facility offers strong support for basic research and the translation of scientific achievements in medicine and life sciences across Shenzhen and the Guangdong-Hong Kong-Macao Greater Bay Area.